Edegra 50mg Tablet

Uses of Edegra 50mg Tablet

• Erectile Dysfunction (impotence)
• Pulmonary arterial hypertension

How does Edegra 50mg Tablet work?

Sildenafil Citrate 50 MG Tablet has Sildenafil which works by relaxing the smooth muscles in the penis and increases blood flow. This helps the penis to harden and leads to an erection. 

Side Effects of Edegra 50mg Tablet

Here are the major and minor side effects associated with Edegra 50mg Tablet:

Major side effects:

• Headache
• Nosebleed
• Indigestion
• Trouble sleeping
• Diarrhea
• Dizziness
• Visual disturbances
• Prolonged and painful erection
• Painful urination
• Ringing or buzzing in the ears
• Deafness

Minor side effects:

• Bloody and cloudy urine
• Burning, numbness, tingling in the arms and feet
• Sensitivity to light
• Excessive tearing of the eye
• Nasal congestion
• Nausea
• Redness of the skin, especially on the face and neck

Quick Suggestions:

• You have been prescribed Edegra 50mg Tablet for the treatment of erectile dysfunction.
• It is best to take it an hour before sexual intercourse. But, you can take it anytime between 30 minutes and 4 hours before sexual activity.
• Do not take it more than once a day.
• Seek medical attention if the erection persists for more than 4 hours after sexual intercourse.
• Do not use Edegra 50mg Tablet if you have recently taken nitrates (medicines used in angina or chest pain).
• Do not take it if you have had a heart attack in the past 3 months, or stroke or heart failure in the past 6 months.

Indication

Edegra 50mg Tablet is categorized as a phosphodiesterase type-5 (PDE 5) inhibitor, primarily prescribed for two distinct purposes. It is mainly employed for the treatment of erectile dysfunction (ED) in adult men and also for managing pulmonary arterial hypertension (high blood pressure in the lungs) in adults. This medication aims to enhance exercise capacity and slow down the progression of clinical symptoms associated with pulmonary hypertension.

The mechanism of Edegra 50mg Tablet involves the relaxation of blood vessels within the penis. This relaxation allows for increased blood flow into the penile tissues, specifically when the individual experiences sexual excitement or arousal. It's essential to note that the effect of Edegra 50mg Tablet is only realized when sexual stimulation is present, as it assists the person in achieving an erection.

Furthermore, Edegra 50mg Tablet also plays a role in widening blood vessels in the lungs, thereby augmenting blood supply to this vital organ. This action serves to alleviate the strain on the heart and contributes to the treatment of pulmonary hypertension.

In summary, Edegra 50mg Tablet operates by promoting blood vessel relaxation in the penis to facilitate an erection during sexual arousal, and concurrently, it relaxes blood vessels in the lungs to improve blood flow and mitigate the impact of pulmonary hypertension.

Pharmacology

• Sildenafil is a selective inhibitor of phosphodiesterase type 5 (PDE5).
• It's used to treat erectile dysfunction (ED).
• Sildenafil enhances the effect of nitric oxide (NO) by inhibiting PDE5.
• PDE5 is responsible for breaking down cGMP in the cavernous body.
• Inhibition of PDE5 leads to cGMP accumulation.
• This causes smooth muscle relaxation in the cavernous body.
• Smooth muscle relaxation increases blood flow to the cavernous body.
• This mechanism enables erections suitable for sexual activity.

Dosage & Administration of Edegra 50mg Tablet

• Recommended dose: 50 mg taken about 1 hour before sexual activity.
• Timing flexibility: Can be taken 30 minutes to 4 hours before sexual activity.
• Dosage adjustment: Depending on effectiveness and tolerability, it can be increased to a maximum of 100 mg or decreased to 25 mg.
• Maximum frequency: It's advised to take it only once per day.
• Administration: Take with or without food, but heavy meals may delay its effect. Do not crush, break, or chew the tablet.
• Dosage frequency: Do not take more than one tablet in a day.
• Sharing medication: Do not give your medicine to others, even if their condition seems similar.
• Timing: Ideally, take the tablet about an hour before sexual activity, with a flexibility of 30 minutes to 4 hours before.
• Seeking medical help: If an erection lasts more than 4 hours after sexual activity, seek medical attention.
• Sexual stimulation: The medicine requires sexual stimulation to work; it doesn't cure erectile dysfunction.
• Lifestyle changes: Consider making lifestyle modifications like quitting smoking, moderating alcohol, maintaining a healthy weight, and exercising alongside taking Sildenafil Citrate 50 MG Tablet.
• Protection against STDs: Remember that the medicine doesn't provide protection against sexually transmitted diseases, so use appropriate safety measures during intercourse.

Interaction

When Sildenafil is taken with organic nitrates for angina, it can cause hypotension. Cimetidine, a drug used to treat gastric ulcers, as well as certain antibiotics like Erythromycin and Rifampicin, and protease inhibitors like Ritonavir and Saquinavir, used to treat HIV infection, may raise Sildenafil levels in the blood

Contraindications

• Allergy
• Cardiovascular Disease
• Kidney Disease
• Eye Disorder

Pregnancy & Lactation

Sildenafil is not recommended for use in women.

Precautions & Warnings

Patients should proceed with caution if they are allergic to any other drugs or any other substances (such as food, preservatives, or dyes), heart or blood vessel problems, or sudden blindness in one or both eyes. If the patient has any of the following diseases, such as diabetes, kidney or liver problems, leukemia, multiple myeloma, any penile disease or malformation, any bleeding disorder such as hemophilia, gastric ulcer, sickle cell anemia, you should be cautious Acting, color vision. Hearing problems, reduced or sudden loss, or any other treatment for impotence.

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children.